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integratori pierpaoli Our products are based on fifty years of scientific research, and on a commitment to always place people at the centre of our interest. We support people’s health through our products, and we know how to do that well. Mission Vision Pierpaoli products are born from the goal of
improving people’s health, compensating for
deficiencies in our organisms that are
increasingly associated with modern lifestyles.
We offer safe, high-quality products, based on fifty years of scientific research. Courage, intellectual freedom and a sense of belonging inspire our way of working, and identify the people we work with. We work so that our development is bound to the
wellbeing of the people we work with.
pierpaoli ico pierpaoli ico integratori piaerpaoli integratori pierpaoli

pierpaoli ico
pierpaoli ico

Mission

Pierpaoli products are born from the goal of improving people’s health, compensating for deficiencies in our organisms that are increasingly associated with modern lifestyles. We offer safe, high-quality products, based on fifty years of scientific research.

Courage, intellectual freedom and a sense of belonging inspire our way of working, and identify the people we work with. We work so that our development is bound to the wellbeing of the people we work with.

pierpaoli ico

Vision

Our products are based on fifty years of scientific research, and on a commitment to always place people at the centre of our interest. We support people’s health through our products, and we know how to do that well.

About us

logo exelyas

The Pierpaoli company identity is based on the research that has proven how hormones and all body molecules closely follow daytime and night-time cycles (circadian rhythms), sun and moon cycles, and seasonal cycles, and that these cycles are at the basis our our health.

According to Pierpaoli’s studies, aging is an evolution process, a “program” like growth and fertility, linked to our genetic makeup and expressed through maintaining and then the progressive deterioration of our hormonal cycles (that are regulated by the nervous system of the hypothalamus-pituitary-pineal gland) brain circuit.

Aging in humans is therefore a genetic program, that is expressed by the circadian rhythms of the hormonal system. In turn, the daytime and night-time hormonal rhythms are under the strict control of the Pineal gland impulses, that integrates and sends messages to the endocrine glands.

The pineal gland controls every moment of our journey: growth, puberty, fertility and progressive or rapid aging. Through the synthesis of molecules (melatonin, trh, etc.) the pineal gland maintains those day-night rhythms that are essential for all organic functions, in particular for the immune defense system.

The pineal gland contributes to the: 

  • balance of hormonal, metabolic and immune functions
  • Maintenance of good metabolic conditions
  • Synchronization of the organism’s physiological cycles

Pierpaoli Culture and Method

Fifty years of Pierpaoli research on the relation between hormonal (neuroendocrine) cycles directed by the pineal gland and aging have proven that intervention is possible to resynchronize the biological aging clock and help to maintain young conditions.

The method is scientific, on which fifty years of Pierpaoli research has been based on the causes and effects of aging. The revolution lies in the proof of a correlation between the nervous, endocrine and hormonal systems, and in the regulatory role played by the pineal gland.

Pierpaoli has conducted years of research and clinical trials on the valuable activity of this gland that regulates our life clock, and has produced several scientific publications and books.

According to Pierpaoli’s studies, aging is a program, and it is the pineal gland that dictates the life cycle. The pineal gland contributes to determining:

  • Balance of hormonal, metabolic and immune functions
  • Maintenance of good metabolic conditions
  • Synchronization of the organism’s physiological cycles

Hormones and many body processes follow daytime/ night-time cycles (circadian rhythms), solar and lunar cycles and seasonal cycles. The pineal gland intervenes in controlling these cycles that are essential for maintaining good health.

Protecting the pineal gland’s functional integrity means maintaining synchronization of biological rhythms and therefore a younger, healthier system.

What we do

Melatonin Pierpaoli

The awareness that the cyclical hormonal structure is synchronized every second by the Pineal gland convinced us that maintaining a state of overall balance in the human body is necessary, and possible, by using biological Molecules and Substances.

Applying scientific research in the fields of neuroendocrinology and immunology (neuroimmunomodulation) and in the realm of autoimmune, neurodegenerative and cardiovascular diseases and in transplant immunology are the starting point for each of our formulations.

At Pierpaoli Exelyas we work to make molecules already present in nature available, that can help the organism in its synchronization of the neuro-endocrine and interhormonal system, combating the aging process, and reducing risk factors of age-related pathologies.

Pierpaoli Exelyas develops, produces and sells dietary supplements, pharmaceutical products and innovative cosmetic products formulated to aid the balance of the biological set up that is the foundation of wellbeing and longevity.

A more efficient immune system, rebalance and resynchronization of the neuro-endocrine system, improvement of the metabolism and quality of sleep, longevity and health are just some of the intentions that we pursue with our work.

Research

Our formulations are created from scientific observations that have emerged and matured through fifty years of research and clinical trials conducted by Professor Pierpaoli and collaborators, and also documented in publications in the most prestigious international scientific journals and described in worldwide best-seller books.

Production Protocol

In order to make Melatonina Zinco-Selenio Pierpaoli® a precise production method was developed in Switzerland in 1999 (pharmaceutical procedure).

The preparation composition was studied to guarantee the precise function, and to produce the physiological effect that the product must have, in accordance with the scientific indications given at the time by Doctor Pierpaoli.

Still today, so many years after the creation of the production protocol of Melatonina Zinco-Selenio Pierpaoli®, each process is carried out strictly following these guidelines.

Themethod and formula for making Pierpaoli products are registered and include precise instructions about how to carry out each stage of the process: which checks to carry out on the materials, the temperature range within which the product must be synthesized, the methods and the times of process controls, how to take samples for testing, and lastly, how to store the products that have not yet been packaged.

Specific indications are given to each lot so that raw materials, packaging and sampling procedures can be approved.

The method states the checks to be carried out during processing and each lot has a processing report.

Production takes place in observance of relative regulations, applying the pharmaceutical method in assessment of risks and dangers, and in adopting necessary control measures for hygiene and healthcare purposes.

Finished product quality is guaranteed by ISO-similar processing procedures or GMP, that guarantee that the finished product’s characteristics correspond to what is required and that it is compliant.

Supervisory procedures are put in place for each lot, aimed at protecting the integrity and safety of the finished product. Some of them provide for:

  • Analysis of raw materials, to make sure the active principles correspond to the ones that are declared and to guarantee the absence of contaminants such as bacteria, pathogens, aflatoxins, heavy metals, pesticides, solvent residues, allergens.
  • Control of environments and surfaces, to check the effectiveness of cleaning procedures, and to prevent and confirm the absence of cross-contamination.
  • Installation of automatic controls in line, to avoid total or part lacks of products, alongside a constant, effective control of processes, carried out by qualified staff in Quality Control, according to procedures acquired by the pharmaceutical field
  • Analytical controls on the finished product and issue of the Certificate of Compliance for product commercialization.

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