



ORIGINAL & EXCLUSIVE FORMULA
by Walter Pierpaoli
Description and properties. Dietary melatonin, zinc and selenium supplement. This formulation is based on 50 years of scientific and clinical research by Walter Pierpaoli on melatonin and the interaction between the structures of the central nervous system and the endocrine and immune systems.
Melatonina Zinco Selenio Pierpaoli® is a product formulated following scientific observations and clinical studies conducted by Prof. Walter Pierpaoli.
Benefits of this formulation
Melatonina Zinco Selenio Pierpaoli® is an immediate-release melatonin formulation, which, taken before going to bed, reduces the time needed to fall asleep, helping to keep the body’s physiological cycles in sync, thus regulating the biological sleep-wake rhythm.
An original formula based on the scientific observations and clinical studies conducted by Prof. Walter Pierpaoli and his team on melatonin and the interaction between the structures of the central nervous system (hypothalamus-pituitary-pineal gland brain circuit) and the endocrine and immune system.
By specifically combining melatonin with zinc and selenium, Melatonina Zinco Selenio Pierpaoli® not only helps restore and maintain control over biological rhythms and promote sleep function, but it also helps protect cells from oxidative stress and support the immune system.

It alleviates the effects of circadian dysrhythmia, lag) (melatonin action)

It supports the immune system and protects cells from oxidative stress (zinc and selenium action)
What is melatonin and why is it important?
Melatonina Zinco Selenio Pierpaoli®: composition
Melatonina Zinco Selenio Pierpaoli® has been developed to achieve peak melatonin release during the night and formulated to meet the body’s physiological function requirements.
- Melatonin. It is a natural molecule. In the human body it is synthesised not only in the pineal gland, but also in numerous other organs and tissues, such as the retina and the intestinal mucosa, where it is used for specific functions.
- Zinc. One of the most important trace elements in the human body, it is involved in the production of more than 200 enzymes required for essential cellular functions such as DNA synthesis, cell division and the proper functioning of the immune system. Zinc absorption decreases as ageing progresses. Its deficiency can lead to increased exposure to infections, reduced ability to concentrate, infertility and other disorders.
- Selenium. A very important mineral for our body, it contributes to normal thyroid and immune system function and is essential for the enzymatic reaction required for the synthesis of glutathione, a very powerful physiological molecule capable of protecting cells from oxidative stress damage.
Why take it
Melatonin contributes to reducing the time needed to fall asleep. This beneficial effect can be obtained by taking 1 mg of melatonin shortly before bedtime.
Melatonin also helps alleviate the effects of jet lag; this beneficial effect can be obtained by taking at least 0.5 mg of melatonin before bedtime on the first day of travel and for a few days after your arrival at destination.
Zinc contributes to protecting cells against oxidative stress and to the normal function of the immune system.
Selenium helps protect cells against oxidative stress.
How to use
We recommend taking 1 tablet of Melatonina Zinco Selenio Pierpaoli® in the evening half an hour before bedtime and preferably between 10 pm and midnight.
Warnings
Do not exceed the recommended daily dose. Supplements are not a substitute for a rich and balanced diet and a healthy lifestyle. Keep out of reach of children under three years of age, do not take during pregnancy, store below 25 °C and keep away from light. Excessive use may cause laxative effects due to the presence of mannitol.
For more information:
Frequently asked questions
Does Melatonina Zinco Selenio Pierpaoli® have side effects?
The use of Melatonin, taken as directed, is safe. It is a generally well-tolerated substance with no particular side effects.
The safety and beneficial effects of melatonin have been confirmed by numerous studies and scientific publications.
Is Melatonina Zinco Selenio Pierpaoli® addictive?
Melatonina Zinco Selenio Pierpaoli®, taken as directed, does not cause dependence or addiction.
By interrupting the exogenous intake of melatonin, the pineal gland resumes synthesis of the molecule in physiological quantities.
Is the effect of Melatonina Zinco Selenio Pierpaoli® immediate?
La Melatonina Zinco Selenio Pierpaoli® is an immediate-release formulation. To promote its beneficial effects, it is advisable to adopt behaviours that favour sleep, such as avoiding smoking and drinking coffee and alcohol in the evening, reducing exposure to bright lights and/or intense noise, reducing the use of video screens (PCs, tablets/mobile phones, etc.) and avoiding large meals and foods that are difficult to digest.
Can Melatonina Zinco Selenio Pierpaoli® be given to children?
As with all dietary supplements, unless specifically indicated otherwise, the product cannot be administered to children under 3 years of age. In addition, in most cases, in the absence of specific disorders, healthy children and adolescents with a lifestyle that does not affect biological circadian (sleep-wake) rhythms usually do not have a melatonin deficiency and therefore, unless otherwise assessed by a specialist, do not need melatonin supplementation.
Why does Melatonina Zinco Selenio Pierpaoli® sometimes have an odd odour?
The odd odour that can sometimes be smelled in Melatonina Zinco Selenio Pierpaoli® tablets is due to the characteristics of the natural, bioavailable excipient used in the formulation, which may have a more or less intense odour. This property does not affect the physical and chemical characteristics of the product.
Does Melatonina Zinco Selenio Pierpaoli® ontain ingredients of animal origin?
We do NOT use ingredients of animal origin for the formulation of Melatonina Zinco Selenio Pierpaoli®.